GI tract tumours
Gene: MUTYHAs discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green.Created: 31 Jul 2019, 12:26 p.m. | Last Modified: 31 Jul 2019, 12:26 p.m.
Panel Version: 1.13
Publications
Variants in this GENE are reported as part of current diagnostic practice
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Comment on list classification: Current diagnostic.Created: 7 Feb 2016, 9:25 p.m.
http://chromium.lovd.nl/LOVD2/colon_cancer/home.php?select_db=MUTYH
Created: 8 Dec 2015, 2:24 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Publications
Source Expert List was added to MUTYH. Source NHS GMS was added to MUTYH. Rating Changed from Green List (high evidence) to Green List (high evidence)
Phenotypes for MUTYH were set to Gastrointestinal and Colorectal Cancer High Risk Adenomas, multiple colorectal 608456
This panel has been formed as a result of merging Familial colon cancer (Version 1.5), Multiple bowel polyps (Version 1.9), Peutz-Jeghers syndrome (Version 0.20) panels and copying the reviews from each panel into this united GI Tract panel
Publications for MUTYH were set to 12853198
Phenotypes for MUTYH were set to Gastrointestinal and Colorectal Cancer High Risk Adenomas, multiple colorectal 608456
MUTYH was added to GI tractpanel. Source: Illumina TruGenome Clinical Sequencing Services MUTYH was added to GI tractpanel. Source: UKGTN MUTYH was added to GI tractpanel. Source: Eligibility statement prior genetic testing
MUTYH was created by ellenmcdonagh
MUTYH was added to GI tractpanel. Sources: Emory Genetics Laboratory,Expert list,Expert Review Green