GI tract tumours

Gene: BRCA1

Red List (low evidence)

BRCA1 (BRCA1, DNA repair associated)
EnsemblGeneIds (GRCh38): ENSG00000012048
EnsemblGeneIds (GRCh37): ENSG00000012048
OMIM: 113705, Gene2Phenotype
BRCA1 is in 26 panels

2 reviews

Ian Tomlinson (University of Oxford)

Red List (low evidence)

Mode of inheritance
Unknown

Ian Frayling (Cardiff University)

Red List (low evidence)

May possibly act as a modifier of colorectal cancer risk, but is not recognised as a major predisposition locus
Created: 8 Dec 2015, 2:12 p.m.

History Filter Activity

12 May 2017, Gel status: 1

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

This panel has been formed as a result of merging Familial colon cancer (Version 1.5), Multiple bowel polyps (Version 1.9), Peutz-Jeghers syndrome (Version 0.20) panels and copying the reviews from each panel into this united GI Tract panel

11 May 2017, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

BRCA1 was added to GI tractpanel. Sources: Emory Genetics Laboratory

11 May 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

BRCA1 was created by ellenmcdonagh