GI tract tumours
Gene: POLD1As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green.Created: 31 Jul 2019, 12:27 p.m. | Last Modified: 31 Jul 2019, 12:27 p.m.
Panel Version: 1.13
Publications
Variants in this GENE are reported as part of current diagnostic practice
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Comment on list classification: Expert review plus literature support.Created: 28 Feb 2016, 3:46 p.m.
Source Expert List was added to POLD1. Source NHS GMS was added to POLD1. Rating Changed from Green List (high evidence) to Green List (high evidence)
This panel has been formed as a result of merging Familial colon cancer (Version 1.5), Multiple bowel polyps (Version 1.9), Peutz-Jeghers syndrome (Version 0.20) panels and copying the reviews from each panel into this united GI Tract panel
Phenotypes for POLD1 were set to {Colorectal cancer, susceptibility to, 10} 612591
Publications for POLD1 were set to 26133394
POLD1 was added to GI tractpanel. Source: Expert Review
POLD1 was added to GI tractpanel. Sources: Expert list,Expert Review Green
POLD1 was created by ellenmcdonagh