GI tract tumours
Gene: CDKN2A
CDKN2A (cyclin dependent kinase inhibitor 2A)
EnsemblGeneIds (GRCh38): ENSG00000147889
EnsemblGeneIds (GRCh37): ENSG00000147889
OMIM: 600160, Gene2Phenotype
CDKN2A is in 12 panels
EnsemblGeneIds (GRCh38): ENSG00000147889
EnsemblGeneIds (GRCh37): ENSG00000147889
OMIM: 600160, Gene2Phenotype
CDKN2A is in 12 panels
1 review
Ian Frayling (Cardiff University)
May possibly act as a modifier of colorectal cancer risk, but no evidence that this is a major predisposition locusCreated: 8 Dec 2015, 2:15 p.m.
Details
- Sources
-
- Emory Genetics Laboratory
- Phenotypes
-
- Gastrointestinal and Colorectal Cancer
- OMIM
- 600160
- Clinvar variants
- Variants in CDKN2A
- Penetrance
- Complete
- Panels with this gene
-
- Inherited pancreatic cancer
- Multiple monogenic benign skin tumours
- Adult solid tumours for rare disease
- Adult solid tumours cancer susceptibility
- GI tract tumours
- Bilateral congenital or childhood onset cataracts
- Familial melanoma
- Cytopenias and congenital anaemias
- Melanoma pertinent cancer susceptibility
- Familial tumours of the nervous system
- Childhood solid tumours
- Pigmentary skin disorders
History Filter Activity
12 May 2017, Gel status: 1
panel promoted to version 1
Sarah Leigh (Genomics England Curator)This panel has been formed as a result of merging Familial colon cancer (Version 1.5), Multiple bowel polyps (Version 1.9), Peutz-Jeghers syndrome (Version 0.20) panels and copying the reviews from each panel into this united GI Tract panel
11 May 2017, Gel status: 1
Added New Source
Ellen McDonagh (Genomics England Curator)CDKN2A was added to GI tractpanel. Sources: Emory Genetics Laboratory
11 May 2017, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)CDKN2A was created by ellenmcdonagh