Inherited prostate cancer
Gene: ATM
ATM (ATM serine/threonine kinase)
EnsemblGeneIds (GRCh38): ENSG00000149311
EnsemblGeneIds (GRCh37): ENSG00000149311
OMIM: 607585, Gene2Phenotype
ATM is in 32 panels
EnsemblGeneIds (GRCh38): ENSG00000149311
EnsemblGeneIds (GRCh37): ENSG00000149311
OMIM: 607585, Gene2Phenotype
ATM is in 32 panels
1 review
Sarah Leigh (Genomics England Curator)
The rating of this gene has been updated to Green and the mode of inheritance set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.Created: 31 Jan 2023, 1:42 p.m. | Last Modified: 31 Jan 2023, 1:42 p.m.
Panel Version: 0.3
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
- Sources
-
- NHS GMS
- Expert Review Green
- OMIM
- 607585
- Clinvar variants
- Variants in ATM
- Penetrance
- None
- Panels with this gene
-
- Familial breast cancer
- Adult solid tumours cancer susceptibility
- Haematological malignancies cancer susceptibility
- Brain cancer pertinent cancer susceptibility
- Hereditary ataxia with onset in adulthood
- Primary ovarian insufficiency
- DDG2P
- Hereditary neuropathy
- Inherited pancreatic cancer
- Haematological malignancies for rare disease
- Adult onset neurodegenerative disorder
- Intellectual disability
- Ataxia telangiectasia - mutation testing
- Adult onset dystonia, chorea or related movement disorder
- Vascular skin disorders
- Childhood solid tumours cancer susceptibility
- Inherited breast cancer and ovarian cancer
- Inherited ovarian cancer (without breast cancer)
- Hereditary neuropathy or pain disorder
- Familial Tumours Syndromes of the central & peripheral Nervous system
- COVID-19 research
- Childhood onset dystonia, chorea or related movement disorder
- Hereditary haemorrhagic telangiectasia
- Hereditary ataxia
- Inherited prostate cancer
- Adult solid tumours for rare disease
- Fetal anomalies
- Primary immunodeficiency or monogenic inflammatory bowel disease
- Sarcoma susceptibility
- Early onset dystonia
- Childhood solid tumours
- Ataxia and cerebellar anomalies - narrow panel
History Filter Activity
31 Jan 2023, Gel status: 3
Created, Added New Source, Set mode of inheritance
Sarah Leigh (Genomics England Curator)gene: ATM was added gene: ATM was added to Inherited prostate cancer. Sources: Expert Review Green,NHS GMS Mode of inheritance for gene: ATM was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted