Dilated Cardiomyopathy (DCM)
Gene: TNNC1Comment when marking as ready: On Manchester diagnostic panelCreated: 11 Feb 2016, 2:21 p.m.
Good functional candidate. Little amino acid variation listed in ExAC data; however, very low pick up in studies done to date. Both DCM and HCM cases reported with segregation in small numbers of family members.Created: 6 Jan 2016, 5:12 p.m.
Variants in this GENE are reported as part of current diagnostic practice
This gene has been classified as Green List (High Evidence).
TNNC1 was added to Dilated Cardiomyopathy (DCM)panel. Sources: UKGTN
Model of inheritance for gene TNNC1 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
TNNC1 was added to Dilated Cardiomyopathy (DCM)panel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Expert list
Model of inheritance for gene TNNC1 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
TNNC1 was added to Dilated Cardiomyopathy (DCM)panel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Expert list
Model of inheritance for gene TNNC1 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
TNNC1 was added to Dilated Cardiomyopathy (DCM)panel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Expert list
TNNC1 was added to Dilated Cardiomyopathy (DCM)panel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Expert list