Primary ovarian insufficiencyGene: FOXO4
Insufficient evidence for inclusion
Created: 9 Jun 2017, 4:16 p.m.
Comment when marking as ready: Marked as red as only one variant reported in patients, ans also found in controls
Created: 22 May 2017, 9:32 a.m.
Not associated with phenotype in OMIM. Has been shown to have a functional role in ovarian physiology. In pubmed, one paper in a Tunisian cohort with POI identified one variant both in cases and controls.
Created: 11 May 2017, 9:56 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
premature ovarian insufficiency
Promoting to Version 1 on 31-05-2017, after internal curation and review.
This gene has been classified as Red List (Low Evidence).
FOXO4 was created by arianna
FOXO4 was added to Early onset familial premature ovarian insufficiencypanel. Sources: Literature