Primary ovarian insufficiency
Gene: YTHDC2Comment on publications: Added new publication submitted by Andrey Gagunashvili. PMID:35138268Created: 22 Feb 2022, 8:41 a.m. | Last Modified: 22 Feb 2022, 8:41 a.m.
Panel Version: 1.64
Comment on list classification: New gene added by Andrey Gagunashvili (UCL Great Ormond Street Institute of Child Health). This gene is not associated with a phenotype in OMIM or Gene2Phenotype. There currently does not appear to be any human cases associated with this gene therefore this gene has been given a Red rating.Created: 28 Sep 2021, 10:55 a.m. | Last Modified: 28 Sep 2021, 10:55 a.m.
Panel Version: 1.48
One more reference on association of YTHDC2 with primary ovarian insufficiency was addedCreated: 15 Feb 2022, 4:26 p.m. | Last Modified: 15 Feb 2022, 4:26 p.m.
Panel Version: 1.63
Sources: Literature, ResearchCreated: 26 Sep 2021, 2:12 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Premature ovarian insufficiency; female infertility; absent puberty; primary amenorrhea
Publications
Publications for gene: YTHDC2 were set to 29033321; 29360036
Gene: ythdc2 has been classified as Red List (Low Evidence).
gene: YTHDC2 was added gene: YTHDC2 was added to Primary ovarian insufficiency. Sources: Literature,Research Mode of inheritance for gene: YTHDC2 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: YTHDC2 were set to 29033321; 29360036 Phenotypes for gene: YTHDC2 were set to Premature ovarian insufficiency; female infertility; absent puberty; primary amenorrhea Penetrance for gene: YTHDC2 were set to Complete Review for gene: YTHDC2 was set to RED