Hereditary spastic paraplegia
Gene: ZFYVE26
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
complex HSP (HSP plus learning difficulties or severe cognitive impairment, extrapyramidal signs, ataxia and thin corpus callosum and/or white matter lesion at brain MR)
Publications
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
ZFYVE26 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
ZFYVE26 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen
Model of inheritance for gene ZFYVE26 was changed to BIALLELIC, autosomal or pseudoautosomal
ZFYVE26 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen
ZFYVE26 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen