Hereditary spastic paraplegia
Gene: SPG7
This gene is on the Hereditary Spastic Paraplagia (HSP) NGS Panel in the UCLH National Hospital for Neurology and Neurosurgery & Institute of Neurology (NHNN) Neurogenetics genetic testing manual.Created: 14 Jun 2016, 9:37 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
complex (HSP plus optic atrophy, ataxia, white matter lesions at brain MRI) and pure HSP
Publications
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
SPG7 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
SPG7 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen
Model of inheritance for gene SPG7 was changed to BIALLELIC, autosomal or pseudoautosomal
SPG7 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen
SPG7 was added to Hereditary spastic paraplegiapanel. Sources: Expert list,Illumina TruGenome Clinical Sequencing Services,UKGTN,Radboud University Medical Center, Nijmegen