Primary ciliary disorders
Gene: ATXN10Comment on mode of inheritance: Lack of phenotypic relevance for SNVs - nucleotide repeat expansion mechanismCreated: 5 Nov 2021, 1:45 p.m. | Last Modified: 5 Nov 2021, 1:45 p.m.
Panel Version: 1.35
Comment on list classification: Removed from the panel due to two reviewer comments.Created: 1 Jun 2018, 9:10 a.m.
Comment on mode of pathogenicity: Nucleotide tandem repeats have been associated with Spinocerebellar ataxia 10 in this gene.Created: 30 Nov 2016, 10:38 a.m.
Gene should be deleted - causes a primary ciliopathy;PCD is a motile ciliopathy, likely unrelated at a functional level.Created: 8 Dec 2015, 5:32 p.m.
Phenotypes
ciliopathies
This is a ciliopathy but not a Primary Ciliary Disorder gene and should be removed from the panelCreated: 8 Dec 2015, 4:25 p.m.
Phenotypes
ciliopathies
Tag currently-ngs-unreportable tag was added to gene: ATXN10.
Mode of inheritance for gene: ATXN10 was changed from to Other
Phenotypes for gene: ATXN10 were changed from ciliopathies to Spinocerebellar ataxia 10, OMIM:603516; Ciliopathies
Tag curated_removed tag was added to gene: ATXN10.
Gene: atxn10 has been removed from the panel.
Mode of pathogenicity for ATXN10 was changed to Other - please provide details in the comments
ATXN10 was added to Primary ciliary disorderspanel. Sources: Emory Genetics Laboratory