As discussed with the GMS Neurology Specialist Test Group webex call 11th July 2019: The Specialist Test Group all agreed that there is only enough evidence to rate this gene Red
Created: 29 Jul 2019, 2:49 p.m. | Last Modified: 29 Jul 2019, 2:49 p.m.
Panel Version: 1.34
Somatic mutations are associated with congenital melanosis, presenting as congenital melanocytic naevus syndrome. 18% of a large cohort had neurological involvement, however hydrocephalus was considered a rare association. Therefore not considered appropriate for this panel (rare, presents in a different clear manner, somatic mutations)
Created: 9 May 2017, 1:22 p.m.
Neurocutaneous melanosis, somatic
Source NHS GMS was added to NRAS.
31.05.2017 - panel revised after internal curation and clinical review.
NRAS was added to Hydrocephaluspanel. Source: Expert Review Red
NRAS was created by helen.brittain
NRAS was added to Hydrocephaluspanel. Sources: Literature