Neuroendocrine cancer pertinent cancer susceptibility

Gene: CDKN1B

Green List (high evidence)

CDKN1B (cyclin dependent kinase inhibitor 1B)
EnsemblGeneIds (GRCh38): ENSG00000111276
EnsemblGeneIds (GRCh37): ENSG00000111276
OMIM: 600778, Gene2Phenotype
CDKN1B is in 11 panels

2 reviews

Ellen McDonagh (Genomics England Curator)

Comment on mode of inheritance: Monoallelic for Multiple endocrine neoplasia, type IV 610755.
Created: 26 Jul 2017, 12:42 p.m.

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Phenotypes
Neuroendocrine cancer

History Filter Activity

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Ellen McDonagh: Comment on mode of inheritance

26 Jul 2017, Gel status: 4

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for CDKN1B was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

26 Jul 2017, Gel status: 4

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

19 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

CDKN1B was added to Neuroendocrine cancerpanel. Sources: Expert list

19 Jul 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

CDKN1B was created by ellenmcdonagh