CDKN1B

cyclin dependent kinase inhibitor 1B
OMIM: 600778, Gene2Phenotype

11 panels

Panel Reviews Mode of inheritance Details
11 panels

Red CDKN1B in Parathyroid Cancer

Level 3: Breast and endocrine
Level 2: Tumour syndromes
Version 1.4

review Not set
Sources
  • UKGTN
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755
  • Pituitary Cancer, Parathyroid and Hypercalcemia

Green CDKN1B in Neuroendocrine cancer pertinent cancer susceptibility

Level 3: Pertinent cancer susceptibility gene panel
Level 2: Cancer Programme
Version 1.2

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755

Green CDKN1B in Thyroid cancer pertinent cancer susceptibility

Level 3: Pertinent cancer susceptibility gene panel
Level 2: Cancer Programme
Version 1.3

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755
  • Thyroid cancer
  • Pituitary adenoma

Green CDKN1B in Adult solid tumours for rare disease

Level 3: Tumour syndromes
Level 2: Tumour syndromes
Version 1.25

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert list
  • Expert Review Green
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755
  • Thyroid cancer
  • Pituitary adenoma

Red CDKN1B in COVID-19 research


Level 2: Viral research
Version 1.80

review Unknown
Sources
  • Expert list
  • OMIM
  • Expert Review Red

Green CDKN1B in Familial hyperparathyroidism


Version 2.14
Latest signed off version: v2.3 (3 Mar 2020)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Illumina TruGenome Clinical Sequencing Services
  • UKGTN
  • Emory Genetics Laboratory
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755

Green CDKN1B in Multiple endocrine tumours

Level 3: Breast and endocrine
Level 2: Tumour syndromes
Version 1.13

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Emory Genetics Laboratory
  • Illumina TruGenome Clinical Sequencing Services
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755

Red CDKN1B in Inherited phaeochromocytoma and paraganglioma

Level 3: Breast and endocrine
Level 2: Tumour syndromes
Version 1.9

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Red
  • Illumina TruGenome Clinical Sequencing Services
Phenotypes
  • Multiple Endocrine Neoplasia

Green CDKN1B in Endocrine neoplasms


Version 1.23
Latest signed off version: v1.3 (15 Oct 2020)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • NHS GMS
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755

Green CDKN1B in Adult solid tumours cancer susceptibility

Level 3: Pertinent cancer susceptibility gene panel
Level 2: Cancer Programme
Version 2.14
Latest signed off version: v2.2 (18 Feb 2020)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • NHS GMS
  • Expert Review Green
  • Expert list
Phenotypes
  • Multiple endocrine neoplasia, type IV, OMIM:610755
  • Thyroid cancer
  • Pituitary adenoma

Red CDKN1B in Hearing loss

Level 3: Non-syndromic hearing loss
Level 2: Hearing and ear disorders
Version 2.200
Latest signed off version: v2.5 (13 Feb 2020)

review Not set
Sources
  • Expert