Adult solid tumours cancer susceptibilityGene: CDKN1B
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene green
Created: 2 Aug 2019, 12:34 p.m. | Last Modified: 2 Aug 2019, 12:34 p.m.
Panel Version: 1.5
This gene was reviewed by Lara Hawkes and Clare Turnbull (Cancer Clinical Team, Genomics England) and there are no changes to make.
Created: 20 Aug 2018, 11:54 a.m.
Comment on mode of inheritance: Changed to monoallelic after feedback from Clare Turnbull.
Created: 27 Jul 2017, 11:04 a.m.
Created: 5 Jul 2017, 12:19 p.m.
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Thyroid cancer; Pituitary adenoma
Source NHS GMS was added to CDKN1B.
Clare Turnbull: Tumor Suppressor.
Mode of inheritance for CDKN1B was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
CDKN1B was added to Adult solid tumourspanel. Source: Expert Review Green
CDKN1B was added to Adult solid tumourspanel. Sources: Expert list
CDKN1B was created by ellenmcdonagh