Adult solid tumours cancer susceptibilityGene: MET
As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene green
Created: 2 Aug 2019, 12:34 p.m. | Last Modified: 2 Aug 2019, 12:34 p.m.
Panel Version: 1.5
Gain of function.
Created: 5 Jul 2017, 12:19 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Renal cell cancer, papillary carcinoma
Mode of pathogenicity
Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype -please provide details in the comments
Source NHS GMS was added to MET.
Clare Turnbull: Gain of function.
Mode of pathogenicity for MET was changed to Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments
MET was added to Adult solid tumourspanel. Source: Expert Review Green
MET was added to Adult solid tumourspanel. Sources: Expert list
MET was created by ellenmcdonagh