Adult solid tumours cancer susceptibility

Gene: RAD51D

Green List (high evidence)

RAD51D (RAD51 paralog D)
EnsemblGeneIds (GRCh38): ENSG00000185379
EnsemblGeneIds (GRCh37): ENSG00000185379
OMIM: 602954, Gene2Phenotype
RAD51D is in 7 panels

2 reviews

Ivone Leong (Genomics England Curator)

Green List (high evidence)

As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that there is enough evidence to rate this gene green
Created: 2 Aug 2019, 12:34 p.m. | Last Modified: 2 Aug 2019, 12:34 p.m.
Panel Version: 1.5

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Phenotypes
Ovarian cancer

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • NHS GMS
  • Expert Review Green
  • Expert list
Phenotypes
  • Ovarian cancer
OMIM
602954
Clinvar variants
Variants in RAD51D
Penetrance
Complete
Panels with this gene

History Filter Activity

2 Aug 2019, Gel status: 3

Added New Source

Ivone Leong (Genomics England Curator)

Source NHS GMS was added to RAD51D.

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Clare Turnbull: Tumor Suppressor. Biallelic ph

7 Aug 2017, Gel status: 4

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for RAD51D was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

7 Aug 2017, Gel status: 4

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for RAD51D was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

5 Jul 2017, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

RAD51D was added to Adult solid tumourspanel. Source: Expert Review Green

5 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

RAD51D was added to Adult solid tumourspanel. Sources: Expert list

5 Jul 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

RAD51D was created by ellenmcdonagh