Adult solid tumours cancer susceptibility

Gene: SPRED1

Red List (low evidence)

SPRED1 (sprouty related EVH1 domain containing 1)
EnsemblGeneIds (GRCh38): ENSG00000166068
EnsemblGeneIds (GRCh37): ENSG00000166068
OMIM: 609291, Gene2Phenotype
SPRED1 is in 12 panels

1 review

Ivone Leong (Genomics England Curator)

Red List (low evidence)

As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that RASopathy associated genes associated with cancer will be included in this panel; however, this gene does not appear to predispose patients to cancer so therefore this has been rated red.
Created: 2 Aug 2019, 12:34 p.m. | Last Modified: 2 Aug 2019, 12:34 p.m.
Panel Version: 1.5
No apparent predisposition to cancer
Created: 2 Aug 2019, 12:34 p.m. | Last Modified: 2 Aug 2019, 12:34 p.m.
Panel Version: 1.5

Publications

History Filter Activity

2 Aug 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: SPRED1 was added gene: SPRED1 was added to Adult solid tumours cancer susceptibility. Sources: NHS GMS Mode of inheritance for gene: SPRED1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: SPRED1 were set to 23875798 Phenotypes for gene: SPRED1 were set to Legius syndrome 611431