Adult solid tumours cancer susceptibility

Gene: PTEN

Green List (high evidence)

PTEN (phosphatase and tensin homolog)
EnsemblGeneIds (GRCh38): ENSG00000171862
EnsemblGeneIds (GRCh37): ENSG00000171862
OMIM: 601728, Gene2Phenotype
PTEN is in 47 panels

1 review

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Tumor Suppressor.
5 Jul 2017, 12:19 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
Cowden syndrome

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Cowden syndrome
OMIM
601728
Clinvar variants
Variants in PTEN
Penetrance
Complete
Panels with this gene

History Filter Activity

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Clare Turnbull: Tumor Suppressor.

5 Jul 2017, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

PTEN was added to Adult solid tumourspanel. Source: Expert Review Green

5 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

PTEN was added to Adult solid tumourspanel. Sources: Expert list

5 Jul 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

PTEN was created by ellenmcdonagh