Catecholaminergic polymorphic VTGene: ANK2
Cardiac arrhythmia, ankyrin-B-related (OMIM 600919), Long QT syndrome 4 (OMIM 600919)
Created: 25 Mar 2019, 4:30 p.m.
No evidence for this gene assoc with CPVT. PMID:27761157.
Created: 25 Mar 2019, 4:27 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Variants in this GENE are reported as part of current diagnostic practice
Comment when marking as ready: This gene should remain red, as the expert reviewer is unsure and no clear evidence for association with CPVT found in OMIM or a publication search.
Created: 18 Jul 2016, 3:17 p.m.
Source South West GLH was added to ANK2. Mode of inheritance for gene ANK2 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
22.07.2016: Panel revised according to reviews and further evidence. Confirmed the final panel with Karen McGuire at the Oxford Medical Genetics Laboratory prior to promoting to version 1.
This gene has been classified as Red List (Low Evidence).
ANK2 was added to Catecholaminergic Polymorphic Ventricular Tachycardiapanel. Sources: Expert list