This Panel is marked as Internal
Genomic imprinting
Gene: WT1
WT1 (Wilms tumor 1)
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 18 panels
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 18 panels
1 review
Sarah Leigh (Genomics England Curator)
WT1-Alt transcript (listed in table S1 in PMID 30794780) does not have a match in HGNC. Known as AWT1 (PMID 14681303) and is the previous name, the HGNC approved name is WT1, which includes this alternative transcript.Created: 22 Dec 2020, 6:10 p.m. | Last Modified: 22 Dec 2020, 6:10 p.m.
Panel Version: 0.26
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, maternally imprinted (paternal allele expressed)
- Sources
-
- Literature
- OMIM
- 607102
- Clinvar variants
- Variants in WT1
- Penetrance
- None
- Publications
- Panels with this gene
-
- Sarcoma cancer susceptibility
- Cytopenias and congenital anaemias
- Differences in sex development
- Structural eye disease
- Wilms tumour with features suggestive of predisposition
- Familial rhabdomyosarcoma
- Childhood solid tumours
- Adult solid tumours for rare disease
- Retinal disorders
- Sarcoma susceptibility
- Unexplained kidney failure in young people
- Intellectual disability
- Adult solid tumours cancer susceptibility
- Proteinuric renal disease
- Fetal anomalies
- DDG2P
- Glaucoma (developmental)
- Childhood solid tumours cancer susceptibility
History Filter Activity
22 Dec 2020, Gel status: 1
Created, Added New Source, Set mode of inheritance, Set publications
Sarah Leigh (Genomics England Curator)gene: WT1 was added gene: WT1 was added to Imprinted Genes. Sources: Literature Mode of inheritance for gene: WT1 was set to MONOALLELIC, autosomal or pseudoautosomal, maternally imprinted (paternal allele expressed) Publications for gene: WT1 were set to 30794780; 14681303; http://igc.otago.ac.nz/home.html