Deafness and congenital structural abnormalitiesGene: FOXI3
Not enough clinical evidence at this stage
Created: 17 Oct 2016, 12:39 p.m.
Mode of inheritance
Mode of pathogenicity
Comment when marking as ready: Not associated with phenotype in OMIM nor G2P / DD. One 2.5Mb interstitial deletion of the short arm of chromosome 2 at band 2p11.2 found in child with congenital aural atresia associated with agenesis of iInternal carotid artery.
Created: 14 Sep 2016, 2:23 p.m.
Congenital aural atresia
Variants in this GENE are reported as part of current diagnostic practice
Comment on list classification: Red on the Bilateral Microtia Version 1.10 panel.
Created: 12 Sep 2016, 2:57 p.m.
FOXI3 is not associated with a phenotype entry in OMIM.
Created: 9 Feb 2016, 5:16 p.m.
Single report. Compelling animal and functional evidence only.
Created: 3 Feb 2016, 5:03 p.m.
26th Oct 2016: the panels Bilateral microtia version 1.10, Ear malformations with hearing impairment version 0.105, and familial hemifacial microsomia version 0.149 gene panels were combined to create this panel. The panel was revised due to expert review, further curation of evidence and internal clinical evaluation. Ready for promotion to version 1.
FOXI3 was added to Deafness and congenital structural abnormalitiespanel. Source: Literature Model of inheritance for gene FOXI3 was set to Unknown
FOXI3 was added to Deafness and congenital structural abnormalitiespanel. Sources: Expert list,Expert Review Red
FOXI3 was created by sleigh