Arthrogryposis
Gene: TNNI2
Comment on mode of inheritance: Confirmed on OMIM.Created: 3 May 2016, 9:28 a.m.
Comment on list classification: Green expert review, found in 3 of the 4 original sources, and >3 unrelated family reports in OMIM.Created: 3 May 2016, 9:28 a.m.
16th Jan 2016: This gene panel was extensively revised with the addition of 101 green genes and review by Alice Gardham. Due to this extensive change to the panel, the decision was made to promote it to the next major version, version 2.
TNNI2 was added to Arthrogryposispanel. Source: UKGTN TNNI2 was added to Arthrogryposispanel. Source: Expert
TNNI2 was added to Arthrogryposispanel. Source: Expert list
Publications for TNNI2 were set to PMID: 16802141; 17380469; 23850728
This gene has been classified as Green List (High Evidence).
Mode of inheritance for TNNI2 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
This gene has been classified as Green List (High Evidence).
TNNI2 was added to Arthrogryposispanel. Sources: Emory Genetics Laboratory
Model of inheritance for gene TNNI2 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Model of inheritance for gene TNNI2 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
TNNI2 was added to Arthrogryposispanel. Sources: Illumina TruGenome Clinical Sequencing Services
TNNI2 was added to Arthrogryposispanel. Sources: Radboud University Medical Center, Nijmegen