This Panel is marked as Internal
Undiagnosed neurocutaneous disorders
Gene: HRAS
HRAS (HRas proto-oncogene, GTPase)
EnsemblGeneIds (GRCh38): ENSG00000174775
EnsemblGeneIds (GRCh37): ENSG00000174775
OMIM: 190020, Gene2Phenotype
HRAS is in 30 panels
EnsemblGeneIds (GRCh38): ENSG00000174775
EnsemblGeneIds (GRCh37): ENSG00000174775
OMIM: 190020, Gene2Phenotype
HRAS is in 30 panels
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Details
- Sources
-
- UKGTN
- Phenotypes
-
- Noonan syndrome
- Costello syndrome, 218040
- OMIM
- 190020
- Clinvar variants
- Variants in HRAS
- Penetrance
- Complete
- Publications
- Panels with this gene
-
- Intellectual disability
- Pigmentary skin disorders
- Embryonal tumour of possible germline origin
- Mosaic skin disorders - deep sequencing
- Sarcoma of possible germline origin
- Fetal hydrops
- Fetal anomalies
- Familial rhabdomyosarcoma
- Pneumothorax - familial
- Monogenic short stature
- Segmental overgrowth disorders - Deep sequencing
- RASopathies
- IUGR and IGF abnormalities
- Hypertrophic cardiomyopathy
- Hereditary neuropathy
- Arthrogryposis
- Early onset or syndromic epilepsy
- Childhood solid tumours cancer susceptibility
- Paediatric or syndromic cardiomyopathy
- Hereditary neuropathy or pain disorder
- Multiple monogenic benign skin tumours
- Sarcoma cancer susceptibility
- Primary lymphoedema
- Cytopenias and congenital anaemias
- Childhood solid tumours
- Sarcoma susceptibility
- Adult solid tumours cancer susceptibility
- Congenital myopathy
- DDG2P
- Neurological segmental overgrowth
History Filter Activity
11 May 2017, Gel status: 1
Set Phenotypes
Rebecca Foulger (Genomics England curator)Phenotypes for HRAS were set to Noonan syndrome; Costello syndrome, 218040
11 May 2017, Gel status: 1
Set publications
Rebecca Foulger (Genomics England curator)Publications for HRAS were set to 26903185
10 Dec 2015, Gel status: 1
Added New Source
Ellen McDonagh (Genomics England Curator)HRAS was added to Undiagnosed neurocutaneous disorderspanel. Sources: UKGTN
10 Dec 2015, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)HRAS was created by ellenmcdonagh