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  3. PTGIS
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Extreme early-onset hypertension

Gene: PTGIS

Red List (low evidence)
PTGIS (prostaglandin I2 synthase)
EnsemblGeneIds (GRCh38): ENSG00000124212
EnsemblGeneIds (GRCh37): ENSG00000124212
OMIM: 601699, Gene2Phenotype
PTGIS is in 1 panel

1 review

Sarah Leigh (Genomics England Curator)

Comment when marking as ready: Associated with phenotype in OMIM. Only one variant reported
Created: 25 Jul 2016, 5:07 p.m.
Comment on mode of inheritance: Multifactorial
Created: 25 Jul 2016, 5:04 p.m.
Created: 25 Jul 2016, 5:07 p.m.

Panel version: 0.93

Details

Mode of Inheritance
Other - please specifiy in evaluation comments
Sources
  • Expert Review Red
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Hypertension, essential, 145500
OMIM
601699
Clinvar variants
Variants in PTGIS
Penetrance
Complete
Panels with this gene

History Filter Activity

3 Aug 2016, Gel status: 1

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

Promoted 03/08/2016

25 Jul 2016, Gel status: 1

Gene classified by Genomics England curator

Sarah Leigh (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

25 Jul 2016, Gel status: 1

Set Mode of Inheritance

Sarah Leigh (Genomics England Curator)

Mode of inheritance for PTGIS was changed to Other - please specifiy in evaluation comments

28 Apr 2015, Gel status: 1

Added New Source

GEL ()

PTGIS was added to Extreme early-onset hypertensionpanel. Sources: Radboud University Medical Center, Nijmegen