Extreme early-onset hypertensionGene: SCNN1G
Comment when marking as ready: Associated with phenotype in OMIM, not G2P. Found in 3/4 sources. One reviewer recommends Green. Only two variants associated with Liddle syndrome, (PMID 177200) reported in the literature.
Created: 8 Jun 2016, 7:32 a.m.
Comment on mode of inheritance: Liddle syndrome, 177200 is AD
Created: 7 Jun 2016, 2:33 p.m.
Comment on phenotypes: Liddle syndrome, 177200 is relevant to this panel
Created: 7 Jun 2016, 2:32 p.m.
"SCNN1GÊ" was submitted by the expert, the likely HGNC-approved term is SCNN1G.
Created: 15 Jul 2015, 11:10 a.m.
This gene has been classified as Green List (High Evidence).
Publications for SCNN1G were set to 7550319; 26537344
Publications for SCNN1G were set to 7550319
Mode of inheritance for SCNN1G was changed to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes for SCNN1G were set to Bronchiectasis with or without elevated sweat chloride 3, 613071; Liddle syndrome, 177200; Pseudohypoaldosteronism, type I, 264350
SCNN1G was added to Extreme early-onset hypertensionpanel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,UKGTN
SCNN1G was added to Extreme early-onset hypertensionpanel. Sources: Expert