Limb disordersGene: FRAS1
Fraser syndrome includes syndactyly as a phenotype (in 62% of pateints - PMID: 12766769). Green for this disorders on several version 1 panels. More than 3 families reported.
Created: 7 Nov 2018, 1:26 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Fraser syndrome 1 219000
Ellen McDonagh: Fraser syndrome includes synda
Gene: fras1 has been classified as Green List (High Evidence).
Source Expert Review Green was added to FRAS1. Mode of inheritance for gene FRAS1 was changed from to BIALLELIC, autosomal or pseudoautosomal Added phenotypes Fraser syndrome 1 219000 for gene: FRAS1 Publications for gene FRAS1 were changed from to 12766769; 17163535; 16894541 Rating Changed from Red List (low evidence) to Green List (high evidence)
FRAS1 was added to Limb disorders panel. Sources: Victorian Clinical Genetics Services
FRAS1 was created by Ellen McDonagh