Parkinson Disease and Complex Parkinsonism
Gene: SNCAIP

SNCAIP (synuclein alpha interacting protein)
EnsemblGeneIds (GRCh38): ENSG00000064692
EnsemblGeneIds (GRCh37): ENSG00000064692
OMIM: 603779, Gene2Phenotype
SNCAIP is in 3 panels

2 reviews

Arianna Tucci (Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square)

Red List (low evidence)

This gene encodes for a SNCA interacting protein, and has been has been sequenced in PD as a candidate gene in several studies. Moslty negative results. Has never been described in PD families.
Created: 14 Dec 2016, 5:27 p.m.

Created: 14 Dec 2016, 5:27 p.m.

Panel version: 0.161

Ellen McDonagh (Genomics England Curator)

Comment on list classification: Not associated with a phenotype in OMIM, and variants previously reported have been reclassified due to identification in controls.
Created: 3 Nov 2016, 5:51 p.m.

Created: 3 Nov 2016, 5:51 p.m.

Panel version: 0.118

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

Expert Review Red
Illumina TruGenome Clinical Sequencing Services

Phenotypes

Parkinson Disease, Dominant/Recessive

OMIM

603779

Clinvar variants

Variants in SNCAIP

Penetrance

Complete

Panels with this gene