Dilated Cardiomyopathy and conduction defects
Gene: MPO

MPO (myeloperoxidase)
EnsemblGeneIds (GRCh38): ENSG00000005381
EnsemblGeneIds (GRCh37): ENSG00000005381
OMIM: 606989, Gene2Phenotype
MPO is in 3 panels

2 reviews

Rebecca Whittington (South West GLH)

Red List (low evidence)

Myeloperoxidase deficiency OMIM#254600 AR; {Alzheimer disease, susceptibility to} OMIM#104300;{Lung cancer, protection against, in smokers}
Created: 25 Mar 2019, 4:30 p.m.

No reference to DCM on HGMD or OMIM or as far as I can see in the literature
Created: 25 Mar 2019, 4:27 p.m.

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Created: 25 Mar 2019, 4:24 p.m.

Panel version: 1.55

Oxford Medical Genetics Laboratory (OUH NHS Foundation Trust)

I don't know

Created: 6 Jan 2016, 5:12 p.m.

Panel version: 0.0

Details

Mode of Inheritance

BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Sources

South West GLH
Radboud University Medical Center, Nijmegen

OMIM

606989

Clinvar variants

Variants in MPO

Penetrance

Complete

Panels with this gene

History Filter Activity

21 Feb 2019, Gel status: 1

Added New Source, Set mode of inheritance

Ellen McDonagh (Genomics England Curator)

Source South West GLH was added to MPO. Mode of inheritance for gene MPO was changed from to BOTH monoallelic and biallelic, autosomal or pseudoautosomal

14 Jul 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

MPO was added to Dilated Cardiomyopathy and conduction defectspanel. Sources: Radboud University Medical Center, Nijmegen

Dilated Cardiomyopathy and conduction defects Gene: MPO