Dilated Cardiomyopathy and conduction defects
Gene: TAZAdded new-gene-name tag, new approved HGNC gene symbol for TAZ is TAFAZZINCreated: 10 May 2022, 3:27 p.m. | Last Modified: 10 May 2022, 3:27 p.m.
Panel Version: 1.77
Barth syndrome OMIM#302060Created: 25 Mar 2019, 4:30 p.m.
Paediatric onset disease. Included in review of DCM genes: Dalin 2017 International Journal of Cardiology 228 (2017) 742748, Hershberger 2013 Nat Rev Cardiol 10:531 and Pugh (2014) Genet Med 16, 601.Created: 25 Mar 2019, 4:27 p.m.
Paediatric onset only - paediatric panel. To date only one TAZ variant detected through panel testing. All other positive from targeted TAZ gene testing.Created: 25 Mar 2019, 4:24 p.m.
Mode of inheritance
X-LINKED: hemizygous mutation in males, biallelic mutations in females
Variants in this GENE are reported as part of current diagnostic practice
Comment when marking as ready: Barth syndrome on DDG2PCreated: 14 Feb 2016, 4:22 p.m.
Tag new-gene-name tag was added to gene: TAZ.
Source South West GLH was added to TAZ. Mode of inheritance for gene TAZ was changed from X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males) to X-LINKED: hemizygous mutation in males, biallelic mutations in females Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene TAZ was changed to X-LINKED: hemizygous mutation in males, may be caused by monoallelic mutations in females
TAZ was added to Dilated Cardiomyopathy and conduction defectspanel. Sources: Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services
TAZ was added to Dilated Cardiomyopathy and conduction defectspanel. Sources: Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services