Monogenic diabetes

Gene: NEUROG3

No list

NEUROG3 (neurogenin 3)
EnsemblGeneIds (GRCh38): ENSG00000122859
EnsemblGeneIds (GRCh37): ENSG00000122859
OMIM: 604882, Gene2Phenotype
NEUROG3 is in 5 panels

2 reviews

Ivone Leong (Genomics England Curator)

Red List (low evidence)

Gene changed to grey status after consultation with Professor Sian Ellard (South West GLH) that this gene is not appropriate for the panel.
Created: 25 Jan 2019, 11:49 a.m.

Sian Ellard (University of Exeter Medical School)

Green List (high evidence)

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Variants in this GENE are reported as part of current diagnostic practice

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Removed
Phenotypes
  • Permanent neonatal diabetes and enteric anendocrinosis
OMIM
604882
Clinvar variants
Variants in NEUROG3
Penetrance
None
Publications
Panels with this gene

History Filter Activity

30 Jan 2019, Gel status: 0

Panel promoted to version 1.0

Ivone Leong (Genomics England Curator)

Ivone Leong: Gene changed to grey status af

25 Jan 2019, Gel status: 0

Added New Source, Status Update

Ivone Leong (Genomics England Curator)

Source Expert Review Removed was added to NEUROG3. Rating Changed from Green List (high evidence) to No List (delete)

18 Dec 2018, Gel status: 4

Set Phenotypes, Set publications

Ellen McDonagh (Genomics England Curator)

Added phenotypes Permanent neonatal diabetes and enteric anendocrinosis for gene: NEUROG3 Publications for gene NEUROG3 were changed from 26288179; 25650326 to 26288179; 25650326; Rubio-Cabezas et al 2011 Diabetes 60:1349-1353

18 Dec 2018, Gel status: 4

Created, Added New Source, Set mode of inheritance, Set publications

Ellen McDonagh (Genomics England Curator)

gene: NEUROG3 was added gene: NEUROG3 was added to Monogenic diabetes. Sources: Expert Review Green Mode of inheritance for gene: NEUROG3 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: NEUROG3 were set to 26288179; 25650326