Monogenic diabetes

Gene: LIPC

No list

LIPC (lipase C, hepatic type)
EnsemblGeneIds (GRCh38): ENSG00000166035
EnsemblGeneIds (GRCh37): ENSG00000166035
OMIM: 151670, Gene2Phenotype
LIPC is in 8 panels

3 reviews

Ivone Leong (Genomics England Curator)

Red List (low evidence)

Gene changed to grey status after consultation with Professor Sian Ellard (South West GLH) that this gene is not appropriate for the panel.
Created: 25 Jan 2019, 11:49 a.m.

Ellen McDonagh (Genomics England Curator)

Red List (low evidence)

Sian Ellard (University of Exeter Medical School)

No evidence to support this being a monogenic diabetes gene - included in error?
Created: 23 Aug 2015, 4:50 p.m.

Details

Mode of Inheritance
Unknown
Sources
  • Expert Review Removed
Phenotypes
  • Hepatic lipase deficiency, 614025
  • [High density lipoprotein cholesterol level QTL 12], 612797
  • {Diabetes mellitus, noninsulin-dependent}, 125853
OMIM
151670
Clinvar variants
Variants in LIPC
Penetrance
None
Panels with this gene

History Filter Activity

30 Jan 2019, Gel status: 0

Panel promoted to version 1.0

Ivone Leong (Genomics England Curator)

Ivone Leong: Gene changed to grey status af

25 Jan 2019, Gel status: 0

Added New Source, Status Update

Ivone Leong (Genomics England Curator)

Source Expert Review Removed was added to LIPC. Rating Changed from Red List (low evidence) to No List (delete)

18 Dec 2018, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: LIPC was added gene: LIPC was added to Monogenic diabetes. Sources: Expert Review Red Mode of inheritance for gene: LIPC was set to Unknown Phenotypes for gene: LIPC were set to Hepatic lipase deficiency, 614025; [High density lipoprotein cholesterol level QTL 12], 612797; {Diabetes mellitus, noninsulin-dependent}, 125853