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  3. FICD
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DDG2P

Gene: FICD

Red List (low evidence)
FICD (FIC domain containing)
EnsemblGeneIds (GRCh38): ENSG00000198855
EnsemblGeneIds (GRCh37): ENSG00000198855
FICD is in 6 panels

1 review

Achchuthan Shanmugasundram (Genomics England Curator)

Red List (low evidence)

The DDG2P confidence category, allelic requirement and molecular mechanism for FICD-related infancy-onset diabetes and neurodevelopmental disorder are limited, biallelic_autosomal and loss of function (PMID:36704923). More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P03557.
Created: 13 Feb 2026, 9:25 p.m. | Last Modified: 13 Feb 2026, 9:25 p.m.
Panel Version: 6.17
The DDG2P confidence category for the disease FICD-related infancy-onset diabetes and neurodevelopmental disorder is limited. The allelic requirement and mutation consequence are biallelic_autosomal and altered gene product structure (PMID: 36704923).
Created: 26 Sep 2024, 8:30 p.m. | Last Modified: 26 Sep 2024, 8:30 p.m.
Panel Version: 4.10

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
FICD-related infancy-onset diabetes and neurodevelopmental disorder

Publications

Mode of pathogenicity
Other

Created: 26 Sep 2024, 8:30 p.m.
Last Modified: 26 Sep 2024, 8:30 p.m.
Panel version: 6.17

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • DD-Gene2Phenotype
  • Expert Review Red
Phenotypes
  • FICD-related infancy-onset diabetes and neurodevelopmental disorder
Clinvar variants
Variants in FICD
Penetrance
None
Publications
Panels with this gene

History Filter Activity

16 Feb 2026, Gel status: 1

Set mode of pathogenicity

Achchuthan Shanmugasundram (Genomics England Curator)

Mode of pathogenicity for gene: FICD was changed from Other to None

26 Sep 2024, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes, Set mode of pathogenicity

Achchuthan Shanmugasundram (Genomics England Curator)

gene: FICD was added gene: FICD was added to DDG2P. Sources: Expert Review Red,DD-Gene2Phenotype Mode of inheritance for gene: FICD was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: FICD were set to 36704923 Phenotypes for gene: FICD were set to FICD-related infancy-onset diabetes and neurodevelopmental disorder Mode of pathogenicity for gene: FICD was set to Other