Hypertrophic cardiomyopathy - teen and adultGene: KLF10
Created: 25 Mar 2019, 4:30 p.m.
6 DM variants on HGMD reported in , but 3 reduced pathogenicity following subsequent review. (pubmed 22234868, 30165862, 23299917)
Created: 25 Mar 2019, 4:27 p.m.
Mode of inheritance
On the Inherited Cardiac Condition Genes panel for Hypertrophic cardiomyopathy reported in: Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition Genes, Pua et al, Journal of Cardiovascular Translational Research, online Feb 2016 (doi:10.1007/s12265-016-9673-5). The panel contains disease-causing, putatively pathogenic, research and phenocopy genes, and it is unclear from the publication whether this gene falls into the disease-causing category. No. of mutations indicated in supplemental table = 6.
Created: 19 Feb 2016, 11:55 a.m.
Source South West GLH was added to KLF10.
KLF10 was added to Hypertrophic Cardiomyopathypanel. Sources: Literature
KLF10 was created by ellenmcdonagh