Hypertrophic cardiomyopathy
Gene: TTN
Cardiomyopathy, familial hypertrophic, 9 (613765)Created: 25 Mar 2019, 4:30 p.m.
Limited evidence for HCMCreated: 25 Mar 2019, 4:27 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Comment on publications: Supports as cause of DCM but not HCMCreated: 11 Feb 2016, 3:17 p.m.
Comment on mode of inheritance: Only strong evidence of causality with biallelic LOF mutationsCreated: 11 Feb 2016, 3:14 p.m.
Suggest removal from HCM panelCreated: 6 Jan 2016, 5:11 p.m.
Source South West GLH was added to TTN. Mode of inheritance for gene TTN was changed from BIALLELIC, autosomal or pseudoautosomal to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
This gene has been classified as Red List (Low Evidence).
Publications for TTN were set to http://www.ncbi.nlm.nih.gov/pubmed/22335739
Mode of inheritance for TTN was changed to BIALLELIC, autosomal or pseudoautosomal
TTN was added to Hypertrophic Cardiomyopathypanel. Sources: Expert list
Model of inheritance for gene TTN was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
TTN was added to Hypertrophic Cardiomyopathypanel. Sources: Emory Genetics Laboratory,Radboud University Medical Center, Nijmegen,Illumina TruGenome Clinical Sequencing Services
Model of inheritance for gene TTN was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
TTN was added to Hypertrophic Cardiomyopathypanel. Sources: Emory Genetics Laboratory,Radboud University Medical Center, Nijmegen,Illumina TruGenome Clinical Sequencing Services
TTN was added to Hypertrophic Cardiomyopathypanel. Sources: Emory Genetics Laboratory,Radboud University Medical Center, Nijmegen,Illumina TruGenome Clinical Sequencing Services