Hypertrophic cardiomyopathy - teen and adult

Gene: NRAS

Red List (low evidence)

NRAS (NRAS proto-oncogene, GTPase)
EnsemblGeneIds (GRCh38): ENSG00000213281
EnsemblGeneIds (GRCh37): ENSG00000213281
OMIM: 164790, Gene2Phenotype
NRAS is in 24 panels

2 reviews

Rebecca Whittington (South West GLH)

Red List (low evidence)

Noonan syndrome 6 (613224)
Created: 25 Mar 2019, 4:30 p.m.
Rasopathy gene. In HGMD mainly associated with Noonans/Costello syndrome
Created: 25 Mar 2019, 4:27 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Oxford Medical Genetics Laboratory (OUH NHS Foundation Trust)

I don't know

History Filter Activity

21 Feb 2019, Gel status: 1

Added New Source, Set mode of inheritance

Ellen McDonagh (Genomics England Curator)

Source South West GLH was added to NRAS. Mode of inheritance for gene NRAS was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

13 Jul 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

NRAS was added to Hypertrophic Cardiomyopathypanel. Sources: Expert list