Intestinal failure or congenital diarrhoea

Gene: ICOS

Green List (high evidence)

ICOS (inducible T-cell costimulator)
EnsemblGeneIds (GRCh38): ENSG00000163600
EnsemblGeneIds (GRCh37): ENSG00000163600
OMIM: 604558, Gene2Phenotype
ICOS is in 6 panels

1 review

Eleanor Williams (Genomics England Curator)

This gene has been added to the panel on the recommendation of the NHS Genomic Medicine Service and should be rated green.
Created: 8 Mar 2022, 11:44 a.m. | Last Modified: 8 Mar 2022, 11:44 a.m.
Panel Version: 1.48


Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
  • Expert Review Green
  • Immunodeficiency, common variable, 1, OMIM:607594
Clinvar variants
Variants in ICOS
Panels with this gene

History Filter Activity

8 Mar 2022, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: ICOS was added gene: ICOS was added to Intestinal failure. Sources: Expert Review Green Mode of inheritance for gene: ICOS was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: ICOS were set to Immunodeficiency, common variable, 1, OMIM:607594