Mitochondrial disorder with complex I deficiency
Gene: NDUFS6

NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6)
EnsemblGeneIds (GRCh38): ENSG00000145494
EnsemblGeneIds (GRCh37): ENSG00000145494
OMIM: 603848, Gene2Phenotype
NDUFS6 is in 9 panels

2 reviews

Ivone Leong (Genomics England Curator)

Green List (high evidence)

Initial gene list and info collated by Carl Fratter (Oxford University Hospitals NHS Trust) January 2019 on behalf of the GMS Mitochondrial specialist test group. Gene Symbol submitted: NDUFS6; Suggested intial gene rating: Green; Information provided: Mode of inheritance and phenotype.
Created: 1 Feb 2019, 4:29 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Mitochondrial complex I deficiency, nuclear type 9, 618232

Created: 1 Feb 2019, 4:29 p.m.

Panel version: 0.3

Shamima Rahman (UCL Institute of Child Health)

Green List (high evidence)

Created: 8 Feb 2016, 10:29 a.m.

Panel version: Imported from Mitochondrial disorders panel version 0.37

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

NHS GMS
Expert Review Green

Phenotypes

Mitochondrial complex I deficiency, nuclear type 9, 618232

OMIM

603848

Clinvar variants

Variants in NDUFS6

Penetrance

None

Panels with this gene

History Filter Activity

1 Feb 2019, Gel status: 4

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: NDUFS6 was added gene: NDUFS6 was added to Mitochondrial disorder with complex I deficiency. Sources: Expert Review Green,NHS GMS Mode of inheritance for gene: NDUFS6 was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: NDUFS6 were set to Mitochondrial complex I deficiency, nuclear type 9, 618232

Mitochondrial disorder with complex I deficiency Gene: NDUFS6