Pigmentary skin disordersGene: PTEN
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
COWDEN SYNDROME 1; CWS1
This gene was part of an initial gene list collated by Thomas Cullup, GOSH and Veronica Kinsler, UCL, 25.Jan.2019 on behalf of the GMS Skin Specialist Test Group. Gene Symbol submitted: PTEN; Suggested initial gene rating: Green; Evidence for inclusion: none provided; Evidence for exclusion: none provided; Technical notes (e.g. non-coding/CNV mutations requiring coverage?): none provided.
Created: 31 Jan 2019, 11:31 a.m.
Added phenotypes COWDEN SYNDROME 1; CWS1 for gene: PTEN Publications for gene PTEN were changed from to 9140396
Source London North GLH was added to PTEN.
gene: PTEN was added gene: PTEN was added to Pigmentary skin disorders. Sources: Expert Review Green,NHS GMS Mode of inheritance for gene: PTEN was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: PTEN were set to Bannayan-Riley-Ruvalcaba syndrome; Cowden syndrome; Epidermal naevi; Melanoma