Haematological malignancies cancer susceptibility
Gene: MAD2L2
MAD2L2 (mitotic arrest deficient 2 like 2)
EnsemblGeneIds (GRCh38): ENSG00000116670
EnsemblGeneIds (GRCh37): ENSG00000116670
OMIM: 604094, Gene2Phenotype
MAD2L2 is in 5 panels
EnsemblGeneIds (GRCh38): ENSG00000116670
EnsemblGeneIds (GRCh37): ENSG00000116670
OMIM: 604094, Gene2Phenotype
MAD2L2 is in 5 panels
1 review
Clare Turnbull (Queen Mary University London)
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- Expert Review Green
- Curated sources
- Phenotypes
-
- Class: BM failure FA, (typ AR)
- Fanconi anemia
- MDS
- AML
- Squamous cell carcinoma: oral, GI, vulvar
- OMIM
- 604094
- Clinvar variants
- Variants in MAD2L2
- Penetrance
- Complete
- Publications
- Panels with this gene
History Filter Activity
7 Sep 2018, Gel status: 4
Panel promoted to version 1.0
Louise Daugherty (Genomics England Curator)Ellen McDonagh: Comment on mode of inheritance
30 Jan 2018, Gel status: 4
Added New Source
Ellen McDonagh (Genomics England Curator)Expert Review Green was added to MAD2L2. Panel: Haematological malignancies pertinent cancer susceptibility
21 Jun 2017, Gel status: 0
Added New Source
Ellen McDonagh (Genomics England Curator)MAD2L2 was added to Haematological malignanciespanel. Sources: Curated sources
21 Jun 2017, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)MAD2L2 was created by ellenmcdonagh