Haematological malignancies cancer susceptibility
Gene: RPL27
The rating of this gene has been updated to Red following NHS Genomic Medicine Service approval.Created: 30 Jan 2023, 11:21 a.m. | Last Modified: 30 Jan 2023, 11:21 a.m.
Panel Version: 3.3
Updating tags to be Q3_22_expert_review and Q3_22_rating so that gene is included in the next GMS report.
See review on the 'Cytopenia - NOT Fanconi anaemia' panel https://panelapp.genomicsengland.co.uk/panels/519/gene/RPL27/ indicating there has only been 1 reported case to date.Created: 5 Oct 2022, 11:26 p.m. | Last Modified: 5 Oct 2022, 11:26 p.m.
Panel Version: 2.36
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Tag Q3_22_rating was removed from gene: RPL27. Tag Q3_22_expert_review was removed from gene: RPL27.
Source NHS GMS was added to RPL27. Source Expert Review Red was added to RPL27. Rating Changed from Green List (high evidence) to Red List (low evidence)
Tag Q3_22_rating tag was added to gene: RPL27. Tag Q3_22_expert_review tag was added to gene: RPL27.
Ellen McDonagh: Comment on mode of inheritance
Expert Review Green was added to RPL27. Panel: Haematological malignancies pertinent cancer susceptibility
RPL27 was created by ellenmcdonagh
RPL27 was added to Haematological malignanciespanel. Sources: Curated sources