Haematological malignancies cancer susceptibility
Gene: STXBP2Comment on list classification: Promoted to Amber for review.Created: 3 Apr 2019, 3:48 p.m.
Gene on a list submitted by Clare Turnbull.
Sources: Expert list, LiteratureCreated: 3 Apr 2019, 3:47 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
risk of lymphoma; Hemophagocytic lymphohistiocytosis, familial, 5 613101
Publications
Phenotypes for gene: STXBP2 were changed from risk of lymphoma; Hemophagocytic lymphohistiocytosis, familial, 5 613101 to risk of lymphoma; predisposition to acute lymphoblastic leukemia (ALL); Hemophagocytic lymphohistiocytosis, familial, 5 613101
Publications for gene STXBP2 were changed from 23100279 to 23100279; 24827398
Gene: stxbp2 has been classified as Amber List (Moderate Evidence).
gene: STXBP2 was added gene: STXBP2 was added to Haematological malignancies cancer susceptibility. Sources: Expert list,Literature Mode of inheritance for gene: STXBP2 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: STXBP2 were set to 23100279 Phenotypes for gene: STXBP2 were set to risk of lymphoma; Hemophagocytic lymphohistiocytosis, familial, 5 613101