Periodic fever syndromes
Gene: IL36RN
IL36RN (interleukin 36 receptor antagonist)
EnsemblGeneIds (GRCh38): ENSG00000136695
EnsemblGeneIds (GRCh37): ENSG00000136695
OMIM: 605507, Gene2Phenotype
IL36RN is in 6 panels
EnsemblGeneIds (GRCh38): ENSG00000136695
EnsemblGeneIds (GRCh37): ENSG00000136695
OMIM: 605507, Gene2Phenotype
IL36RN is in 6 panels
1 review
Alice Gardham (Genomics England)
Comment on list classification: Recognised by Royal Free Periodic Fever service as a cause of inherited fevers.Created: 2 Feb 2017, 11:23 a.m.
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- Expert Review Green
- Other
- Phenotypes
-
- Psoriasis 14, pustular, OMIM:614204
- Recurrent flares of pustular rash with fever
- OMIM
- 605507
- Clinvar variants
- Variants in IL36RN
- Penetrance
- Complete
- Panels with this gene
History Filter Activity
10 Jan 2022, Gel status: 3
Set Phenotypes
Arina Puzriakova (Genomics England Curator)Phenotypes for gene: IL36RN were changed from Psoriasis 14, pustular, 614204; DITRA; recurrent flares of pustular rash with fever to Psoriasis 14, pustular, OMIM:614204; Recurrent flares of pustular rash with fever
22 Feb 2017, Gel status: 4
panel promoted to version 1
Rebecca Foulger (Genomics England curator)22nd February 2017: Promoted to V1. Panel was reviewed by Tracy Briggs and Alice Gardham. Panel was revised according to expert review and additional curation.
2 Feb 2017, Gel status: 4
Gene classified by Genomics England curator
Alice Gardham (Genomics England)This gene has been classified as Green List (High Evidence).
1 Feb 2017, Gel status: 1
Gene classified by Genomics England curator
Alice Gardham (Genomics England)This gene has been classified as Red List (Low Evidence).
17 Jan 2017, Gel status: 0
Added New Source
Rebecca Foulger (Genomics England curator)IL36RN was added to Periodic fever syndromespanel. Sources: Other
17 Jan 2017, Gel status: 0
Created
Rebecca Foulger (Genomics England curator)IL36RN was created by rfoulger