Periodic fever syndromes

Gene: IL36RN

Green List (high evidence)

IL36RN (interleukin 36 receptor antagonist)
EnsemblGeneIds (GRCh38): ENSG00000136695
EnsemblGeneIds (GRCh37): ENSG00000136695
OMIM: 605507, Gene2Phenotype
IL36RN is in 6 panels

1 review

Alice Gardham (Genomics England)

Comment on list classification: Recognised by Royal Free Periodic Fever service as a cause of inherited fevers.
Created: 2 Feb 2017, 11:23 a.m.

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
Phenotypes
  • Psoriasis 14, pustular, 614204
  • DITRA
  • recurrent flares of pustular rash with fever
OMIM
605507
Clinvar variants
Variants in IL36RN
Penetrance
Complete
Panels with this gene

History Filter Activity

22 Feb 2017, Gel status: 4

panel promoted to version 1

Rebecca Foulger (Genomics England curator)

22nd February 2017: Promoted to V1. Panel was reviewed by Tracy Briggs and Alice Gardham. Panel was revised according to expert review and additional curation.

2 Feb 2017, Gel status: 4

Gene classified by Genomics England curator

Alice Gardham (Genomics England)

This gene has been classified as Green List (High Evidence).

1 Feb 2017, Gel status: 1

Gene classified by Genomics England curator

Alice Gardham (Genomics England)

This gene has been classified as Red List (Low Evidence).

17 Jan 2017, Gel status: 0

Added New Source

Rebecca Foulger (Genomics England curator)

IL36RN was added to Periodic fever syndromespanel. Sources: Other

17 Jan 2017, Gel status: 0

Created

Rebecca Foulger (Genomics England curator)

IL36RN was created by rfoulger