Unexplained young onset end-stage renal disease
Gene: DLG5
This gene has been added with green rating to R257 Unexplained young onset end-stage renal disease panel as it has already been rated green in Renal ciliopathies panel (https://panelapp.genomicsengland.co.uk/panels/725/).Created: 11 Jan 2024, 10:04 a.m. | Last Modified: 11 Jan 2024, 10:04 a.m.
Panel Version: 3.21
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
DLG5-associated developmental disorder (biallelic); DLG5-associated developmental disorder (monoallelic)
Phenotypes for gene: DLG5 were changed from DLG5-associated developmental disorder (monoallelic); DLG5-associated developmental disorder (biallelic) to Yuksel-Vogel-Bauser syndrome, OMIM:620703
Tag Q4_23_promote_green tag was added to gene: DLG5.
gene: DLG5 was added gene: DLG5 was added to Unexplained young onset end-stage renal disease. Sources: Expert Review Amber,NHS GMS Mode of inheritance for gene: DLG5 was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal Phenotypes for gene: DLG5 were set to DLG5-associated developmental disorder (monoallelic); DLG5-associated developmental disorder (biallelic)