Groopman et al 2019 - Genes with diagnostic variants
Gene: REN

REN (renin)
EnsemblGeneIds (GRCh38): ENSG00000143839
EnsemblGeneIds (GRCh37): ENSG00000143839
OMIM: 179820, Gene2Phenotype
REN is in 7 panels

1 review

Eleanor Williams (Genomics England Curator)

I don't know

From Groopman et al 2019 Table S7. Gene symbol: REN; Inheritance: AD; Clinical diagnosis: Tubulointerstitial disease; Genetic diagnosis: Autosomal dominant tubulointerstitial kidney disease, REN-associated; OMIM phenotype MIM No.: 613092; Number of cases: 1
Created: 2 Jul 2019, 9:46 p.m. | Last Modified: 2 Jul 2019, 9:46 p.m.

Panel Version: 0.4

Created: 2 Jul 2019, 9:46 p.m.
Last Modified: 2 Jul 2019, 9:46 p.m.
Panel version: 0.4

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

Expert Review Red
Expert review red
Literature

Phenotypes

Tubulointerstitial disease
MIM 613092
Autosomal dominant tubulointerstitial kidney disease, REN-associated

OMIM

179820

Clinvar variants

Variants in REN

Penetrance

None

Panels with this gene

History Filter Activity

2 Jul 2019, Gel status: 1

Added New Source

Eleanor Williams (Genomics England Curator)

Source Expert Review Red was added to REN.

2 Jul 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Eleanor Williams (Genomics England Curator)

gene: REN was added gene: REN was added to Groopman et al 2019 - Genes with diagnostic variants. Sources: Literature,Expert review red Mode of inheritance for gene: REN was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: REN were set to Tubulointerstitial disease; MIM 613092; Autosomal dominant tubulointerstitial kidney disease, REN-associated

Groopman et al 2019 - Genes with diagnostic variants Gene: REN