Sudden cardiac death - previous panel
Gene: CRYAB

CRYAB (crystallin alpha B)
EnsemblGeneIds (GRCh38): ENSG00000109846
EnsemblGeneIds (GRCh37): ENSG00000109846
OMIM: 123590, Gene2Phenotype
CRYAB is in 13 panels

1 review

Ellen McDonagh (Genomics England Curator)

I don't know

This gene was part of an initial gene list collated by Matthew Edwards Royal Brompton Hospital sent 16th Jan 2019 on behalf of the London South GLH for review by the GMS Cardiology Specialist Group. Only gene symbol from the Royal Brompton gene panel was provided - suggested initial gene rating and evidence for inclusion not provided with the list.
Created: 20 Feb 2019, 2:17 p.m.

Created: 20 Feb 2019, 2:17 p.m.

Panel version: Imported from Molecular autopsy panel version 0.86

Details

Mode of Inheritance

Unknown

Sources

Expert Review Amber
London South GLH
London South GLH
Expert Review Amber

Phenotypes

Myopathy, myofibrillar, fatal infantile hypertrophy, alpha B crystallin related, 613869
Cardiomyopathy, dilated, 1II,

OMIM

123590

Clinvar variants

Variants in CRYAB

Penetrance

None

Panels with this gene

History Filter Activity

9 Sep 2019, Gel status: 2

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: CRYAB was added gene: CRYAB was added to Sudden cardiac death. Sources: London South GLH,Expert Review Amber Mode of inheritance for gene: CRYAB was set to Unknown Phenotypes for gene: CRYAB were set to Myopathy, myofibrillar, fatal infantile hypertrophy, alpha B crystallin related, 613869; Cardiomyopathy, dilated, 1II,

Sudden cardiac death - previous panel Gene: CRYAB