Sudden cardiac death - previous panel
Gene: KCNJ8

KCNJ8 (potassium voltage-gated channel subfamily J member 8)
EnsemblGeneIds (GRCh38): ENSG00000121361
EnsemblGeneIds (GRCh37): ENSG00000121361
OMIM: 600935, Gene2Phenotype
KCNJ8 is in 6 panels

1 review

Ellen McDonagh (Genomics England Curator)

I don't know

This gene was part of an initial gene list collated by Matthew Edwards Royal Brompton Hospital sent 16th Jan 2019 on behalf of the London South GLH for review by the GMS Cardiology Specialist Group. Only gene symbol from the Royal Brompton gene panel was provided - suggested initial gene rating and evidence for inclusion not provided with the list.
Created: 20 Feb 2019, 2:17 p.m.

Created: 20 Feb 2019, 2:17 p.m.

Panel version: Imported from Molecular autopsy panel version 0.86

Details

Mode of Inheritance

Unknown

Sources

Expert Review Amber
London South GLH
London South GLH
Expert Review Amber

Phenotypes

short qt
arrhythmia
ventricular tachycardia
atrial fibrillation
Brugada/Brugada like syndrome
Sudden infant death syndrome
?Ventricular fibrillation

OMIM

600935

Clinvar variants

Variants in KCNJ8

Penetrance

None

Publications

19120683

Mode of Pathogenicity

Other

Panels with this gene

History Filter Activity

9 Sep 2019, Gel status: 2

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes, Set mode of pathogenicity

Ivone Leong (Genomics England Curator)

gene: KCNJ8 was added gene: KCNJ8 was added to Sudden cardiac death. Sources: London South GLH,Expert Review Amber Mode of inheritance for gene: KCNJ8 was set to Unknown Publications for gene: KCNJ8 were set to 19120683 Phenotypes for gene: KCNJ8 were set to short qt; arrhythmia; ventricular tachycardia; atrial fibrillation; Brugada/Brugada like syndrome; Sudden infant death syndrome; ?Ventricular fibrillation Mode of pathogenicity for gene: KCNJ8 was set to Other

Sudden cardiac death - previous panel Gene: KCNJ8