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Childhood onset dystonia, chorea or related movement disorder

Gene: MT-TC

No list

MT-TC (mitochondrially encoded tRNA cysteine)
EnsemblGeneIds (GRCh38): ENSG00000210140
EnsemblGeneIds (GRCh37): ENSG00000210140
OMIM: 590020, Gene2Phenotype
MT-TC is in 5 panels

2 reviews

Eleanor Williams (Genomics England Curator)

Comment on list classification: Mitochondrial gene removed from the panel at the request of NHS England following discussion at a Rare Disease workshop. Rating changed from green to grey.
Created: 18 Aug 2020, 3:34 p.m. | Last Modified: 18 Aug 2020, 3:54 p.m.
Panel Version: 1.45

James Polke (Neurogenetics Laboratory, Institute of Neurology, London)

Green List (high evidence)

mitochondrial - suggested inclusion by Huw and Raquel
Created: 9 Jul 2019, 4:24 p.m. | Last Modified: 9 Jul 2019, 4:24 p.m.
Panel Version: 0.9

Details

Mode of Inheritance
MITOCHONDRIAL
Sources
  • Expert Review Removed
  • London North GLH
Phenotypes
  • DYSTONIA, MITOCHONDRIAL
Tags
curated_removed
OMIM
590020
Clinvar variants
Variants in MT-TC
Penetrance
None
Panels with this gene

History Filter Activity

26 Feb 2021, Gel status: 0

Added Tag

Arina Puzriakova (Genomics England Curator)

Tag curated_removed tag was added to gene: MT-TC.

18 Aug 2020, Gel status: 0

Entity classified by Genomics England curator

Eleanor Williams (Genomics England Curator)

Gene: mt-tc has been removed from the panel.

8 Dec 2019, Gel status: 3

Set Phenotypes

Louise Daugherty (Genomics England Curator)

Phenotypes for gene: MT-TC were changed from to DYSTONIA, MITOCHONDRIAL

6 Dec 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Ellen McDonagh (Genomics England Curator)

gene: MT-TC was added gene: MT-TC was added to Childhood onset dystonia or chorea or related movement disorder. Sources: London North GLH,Expert Review Green Mode of inheritance for gene gene: MT-TC was set to MITOCHONDRIAL