| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Cholestasis v0.21 | NOTCH2 | Ivone Leong Marked gene: NOTCH2 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cholestasis v0.21 | NOTCH2 | Ivone Leong Added comment: Comment when marking as ready: As discussed in the GMS Gastrohepatology Specialist Test Group webex call 14th Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cholestasis v0.21 | NOTCH2 | Ivone Leong Gene: notch2 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cholestasis v0.10 | NOTCH2 |
Ivone Leong Source Other was added to NOTCH2. Mode of inheritance for gene NOTCH2 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Added phenotypes Alagille syndrome 2; Neonatal and Adult Cholestasis for gene: NOTCH2 Publications for gene NOTCH2 were changed from to 22209762; 16773578 |
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| Cholestasis v0.4 | NOTCH2 |
Ivone Leong Source Expert Review Green was added to NOTCH2. Rating Changed from Red List (low evidence) to Green List (high evidence) |
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| Cholestasis v0.3 | NOTCH2 | Ivone Leong reviewed gene: NOTCH2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cholestasis v0.2 | NOTCH2 |
Ivone Leong gene: NOTCH2 was added gene: NOTCH2 was added to Cholestasis. Sources: NHS GMS Mode of inheritance for gene: NOTCH2 was set to |
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